We support gold standard studies with double-blind, placebo controlled, randomized trials. Studies including clinical trials may involve the scientific testing of drug or drugs, surgery, medical devices or new methods of diagnosis. We object to studies in which pharmaceutical companies or other corporate sponsors of medical research contribute to trial design; have access to trial data or are permitted to access trial data; or review or interpret trial results prior to publication in medical journals. Corporate sponsors of medical studies should not be able to withhold publication in medical journals if results were negative. Sponsors of studies should utilize Good Clinical Practice (GCP). Both positive and negative results of studies must be reported.